Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23476597 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HTR1ATDP1GAAMEN1 | |
| SCHEMBL16552327 | 0.84 | PLG (0.47) | SMN1; SMN2HTR1AGAAMEN1KMT2A | |
| SCHEMBL535579 | 0.84 | PLG (0.47) | SMN1; SMN2HTR1AGAAMEN1KMT2A | |
| SCHEMBL16964802 | 0.82 | HTR1A (0.43) | SMN1; SMN2HTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL10082604 | 0.82 | HTT (0.37) | SMN1; SMN2HTR1ALMNABACE1BACE2 | |
| SCHEMBL16072051 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2TDP1GAAMEN1APEX1 | |
| SCHEMBL744123 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2TDP1GAAMEN1APEX1 | |
| SCHEMBL24829512 | 0.81 | HTR1A (0.35) | SMN1; SMN2HTR1AKMT2AALDH1A1LMNA | |
| SCHEMBL24287595 | 0.79 | CYP1A2 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20056975 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2TDP1GAAMEN1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019002875-A1 | COMPOUNDS COMPRISING STAPLED OR STITCHED PEPTIDES FOR IMPROVED DRUG DELIVERY | SUTURA THERAPEUTICS LTD (TC) | 2019-01-03 | — | — | WO | disclosed |
| WO-2017109494-A1 | BIOLOGICALLY ACTIVE COMPOUND CONJUGATED TO A STAPLED OR STITCHED PEPTIDE | SUTURA THERAPEUTICS LTD (TC) | 2017-06-29 | — | — | WO | disclosed |
| US-20160114052-A1 | POTENT CONJUGATES AND HYDROPHILIC LINKERS | IMMUNOGEN, INC. (US) | 2016-04-28 | — | — | US | disclosed |
| US-9150649-B2 | Potent conjugates and hydrophilic linkers | IMMUNOGEN, INC. (US) | 2015-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114052-A1 | POTENT CONJUGATES AND HYDROPHILIC LINKERS | CD44, EPCAM, ABCG2 | SMN1; SMN2 3022/4885HTR1A 3653/4885TDP1 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.