Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24662249 | 1.00 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13701461 | 0.94 | SLC6A3 (0.61) | SLC6A3 | |
| SCHEMBL29640045 | 0.94 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL22832435 | 0.94 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL30902994 | 0.93 | SLC6A3 (0.62) | SLC6A3 | |
| SCHEMBL27336288 | 0.93 | SLC6A3 (0.62) | SLC6A3 | |
| SCHEMBL30872136 | 0.81 | SLC6A9 (0.42) | — | |
| SCHEMBL15568747 | 0.81 | SLC6A9 (0.42) | — | |
| SCHEMBL17145458 | 0.81 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28628509 | 0.81 | SLC6A3 (0.60) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4426691-A1 | LACTAMS AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech, Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118201921-A | Lactams as CBL-B inhibitors selective for C-CBL | 基因泰克公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023081853-A1 | LACTAMS AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | GENENTECH, INC. (US) | 2023-05-11 | — | — | WO | disclosed |