Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000092 | 0.81 | CYP2A6 (0.40) | KEAP1CYP2A6GPR183AXLDAO | |
| SCHEMBL4073976 | 0.81 | CYP2A6 (0.52) | KEAP1CYP2A6GPR183AXLDAO | |
| SCHEMBL30460284 | 0.81 | CYP2A6 (0.52) | KEAP1CYP2A6GPR183AXLDAO | |
| SCHEMBL28569699 | 0.77 | RELA (0.52) | GPR183NFE2L2HPGDMAOBMAPT | |
| SCHEMBL30697897 | 0.74 | LMNA (0.52) | KEAP1CYP2A6GPR183AXLLMNA | |
| SCHEMBL475358 | 0.74 | LMNA (0.52) | KEAP1CYP2A6GPR183AXLLMNA | |
| SCHEMBL23245359 | 0.73 | GPR183 (0.38) | KEAP1CYP2A6GPR183AXLLMNA | |
| SCHEMBL8545404 | 0.73 | KDM4E (0.51) | GPR183LMNAHPGDMAOBMAPT | |
| SCHEMBL23245362 | 0.73 | GPR183 (0.38) | KEAP1CYP2A6GPR183AXLLMNA | |
| SCHEMBL8545402 | 0.73 | KDM4E (0.51) | GPR183LMNAHPGDMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927224-A1 | Receptor antagonists | Proximagen Limited (GB) | 2015-10-07 | — | — | EP | disclosed |