SCHEMBL17147126

SCHEMBL17147126

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.59
▸ NPY1R P25929 6/20 0.59
▸ NPY2R P49146 5/20 0.59
▸ NPY5R Q15761 4/20 0.59
▸ OPRD1 P41143 3/20 0.55
▸ FOLH1 Q04609 1/20 0.54
▸ ACE P12821 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863542 0.94 OPRD1 (0.58) NPY4RNPY1RNPY2RNPY5ROPRD1
SCHEMBL29365670 0.89 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5ROPRD1
SCHEMBL30656945 0.89 NPY4R (0.57) NPY4RNPY1RNPY2RNPY5ROPRD1
SCHEMBL9822809 0.89 FOLH1 (0.69) NPY4RNPY1RNPY2ROPRD1FOLH1
SCHEMBL14940816 0.89 FOLH1 (0.69) NPY4RNPY1RNPY2ROPRD1FOLH1
SCHEMBL29532240 0.89 FOLH1 (0.69) NPY4RNPY1RNPY2ROPRD1FOLH1
Hydrochloric Acid SCHEMBL30698091 0.88 FOLH1 (0.67) NPY4RNPY1RNPY2ROPRD1FOLH1
SCHEMBL5552838 0.88 FCER2 (0.48) NPY4RNPY1RNPY2RNPY5ROPRD1
SCHEMBL12038997 0.88 LTA4H (0.62) —
SCHEMBL12057953 0.88 LTA4H (0.62) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190883-A1 STABLE PEPTIDES HAVING RENALASE AGONIST ACTIVITY PERSONAL THERAPEUTICS, LLC 2023-06-22 — — US claimed
EP-4157307-A2 STABLE PEPTIDES HAVING RENALASE AGONIST ACTIVITY Bessor Pharma, LLC (US) 2023-04-05 — — EP claimed
WO-2025034944-A9 METHODS AND COMPOSITIONS FOR PROLONGED RENALASE AGONIST ACTIVITY YALE UNIVERSITY (US) 2025-03-13 — — WO disclosed
WO-2025034944-A1 METHODS AND COMPOSITIONS FOR PROLONGED RENALASE AGONIST ACTIVITY YALE UNIVERSITY (US) 2025-02-13 — — WO disclosed
US-20230190883-A1 STABLE PEPTIDES HAVING RENALASE AGONIST ACTIVITY PERSONAL THERAPEUTICS, LLC 2023-06-22 — — US disclosed
EP-2927241-A1 TDF-related compounds and analogs thereof Thrasos Innovation, Inc. (CA) 2015-10-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190883-A1 STABLE PEPTIDES HAVING RENALASE AGONIST ACTIVITY TMPRSS2, ANPEP, ACE2 NPY4R 2033/4885NPY1R 928/4885NPY2R 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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