SCHEMBL17147338

SCHEMBL17147338

CCCC1CCC(C2CCC(C(=O)OC(CC)C3CCCCC3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TLR4 O00206 1/20 0.33
CCR2 P41597 1/20 0.31
FKBP1A P62942 2/20 0.31
SHBG P04278 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL883746 0.91 CTSK (0.42) CTSKCCR2CYP1A2
SCHEMBL14451346 0.89 SHBG (0.33) ALDH1A1FKBP1ASHBG
SCHEMBL12152925 0.85 EPHX1 (0.35) CTSKALDH1A1FKBP1ASHBG
SCHEMBL9607899 0.85 SHBG (0.35) CTSKALDH1A1FKBP1ASHBG
SCHEMBL18476305 0.82 SHBG (0.31) ALDH1A1SHBG
SCHEMBL13767051 0.81 CTSK (0.40) CTSKCCR2CYP1A2
SCHEMBL10022764 0.81 ALDH1A1 (0.36) ALDH1A1SHBG
SCHEMBL13239386 0.78 TSHR (0.37) CTSK
SCHEMBL13095730 0.78 TP53 (0.43) CTSKCCR2CYP1A2
SCHEMBL10845385 0.78 TLR4 (0.36) CTSKALDH1A1TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9611428-B2 Liquid-crystalline medium and electro-optical liquid-crystal display MERCK PATENT GMBH (DE) 2017-04-04 US disclosed
US-9611428-B2 Liquid-crystalline medium and electro-optical liquid-crystal display MERCK PATENT GMBH (DE) 2017-04-04 US disclosed
US-20150284635-A1 LIQUID-CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-10-08 US disclosed
US-20150284635-A1 LIQUID-CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-10-08 US disclosed