Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.53 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147670 | 1.00 | HTR2C (0.53) | HTR2CKDM1ARCOR1HTR2AHTR2B | |
| SCHEMBL19101157 | 1.00 | HTR2C (0.53) | HTR2CKDM1ARCOR1HTR2AHTR2B | |
| SCHEMBL19102566 | 0.83 | NOTUM (0.37) | HTR2CKDM1AHTR2AHTR2BCHRNB2 | |
| SCHEMBL17151050 | 0.83 | NOTUM (0.37) | HTR2CKDM1AHTR2AHTR2BCHRNB2 | |
| SCHEMBL18848434 | 0.81 | HTR2C (0.55) | HTR2CKDM1ARCOR1HTR2AHTR2B | |
| SCHEMBL12875674 | 0.81 | HTR2C (0.55) | HTR2CKDM1ARCOR1HTR2AHTR2B | |
| SCHEMBL25246705 | 0.79 | HTR2C (0.53) | HTR2C | |
| SCHEMBL25025483 | 0.79 | HTR2C (0.53) | HTR2C | |
| SCHEMBL19733862 | 0.79 | HTR2C (0.53) | HTR2CKDM1ARCOR1MAOBCHRNB2 | |
| SCHEMBL25024467 | 0.79 | HTR2C (0.53) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422380-B2 | Non-bridged metallocene complexes for the polymerization of olefins | Basell Polyolefine Wesseling (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | PCBP1, PARG, PARN | HTR2C 3282/4885KDM1A 3091/4885RCOR1 4260/4885 |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | MAOA, MPO, PARP1 | HTR2C 1192/4885KDM1A 526/4885RCOR1 4302/4885 |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | PCBP1, MORF4L1, PPIL4 | HTR2C 4249/4885KDM1A 3026/4885RCOR1 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.