Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12620335 | 0.86 | NLRP3 (0.42) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL8394084 | 0.81 | CYP19A1 (0.44) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL24299728 | 0.77 | CYP19A1 (0.41) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL10192292 | 0.77 | CYP19A1 (0.41) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL18981060 | 0.76 | CYP19A1 (0.40) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL17147749 | 0.76 | CYP19A1 (0.40) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL18981114 | 0.76 | CYP19A1 (0.40) | CYP19A1CYP2D6CYP2C9CYP2C19STAT3 | |
| SCHEMBL9240777 | 0.71 | MAPT (0.43) | CYP2D6CYP2C9CYP2C19STAT3NLRP3 | |
| SCHEMBL8629540 | 0.71 | MAPT (0.43) | CYP2D6CYP2C9CYP2C19STAT3NLRP3 | |
| SCHEMBL8631899 | 0.71 | MAPT (0.43) | CYP2D6CYP2C9CYP2C19STAT3NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150336919-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | CHO DANG PHARM. CO., LTD. (KR) | 2015-11-26 | — | — | US | disclosed |
| US-20150336919-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | CHO DANG PHARM. CO., LTD. (KR) | 2015-11-26 | — | — | US | disclosed |
| US-20150299155-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | CHO DANG PHARM. CO., LTD. | 2015-10-22 | — | — | US | disclosed |
| US-20150299155-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | CHO DANG PHARM. CO., LTD. | 2015-10-22 | — | — | US | disclosed |
| US-20150284353-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | CHO DANG PHARM, CO., LTD. a corporation | 2015-10-08 | — | — | US | disclosed |
| US-20150284353-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | CHO DANG PHARM, CO., LTD. a corporation | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336919-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | SI, VIP, PGC | CYP19A1 675/4885CYP2D6 667/4885CYP2C9 225/4885 |
| US-20150284353-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | SI, VIP, GGPS1 | CYP19A1 616/4885CYP2D6 710/4885CYP2C9 265/4885 |
| US-20150299155-A1 | Sesquiterpene lactone-based pharmaceutical composition for treating gastrointestinal diseases | SI, VIP, PGC | CYP19A1 675/4885CYP2D6 667/4885CYP2C9 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.