SCHEMBL17148017

SCHEMBL17148017

COCOc1ccc2ccccc2c1-c1c(OCOC(C)=O)ccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
PTGS2 P35354 5/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALOX5 P09917 1/20 0.41
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PTPN1 P18031 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446528 0.87 MAPT (0.63) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL29820187 0.87 MAPT (0.63) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL17148019 0.82 MAPT (0.47) MAPTPTGS2ALOX5HPGD
SCHEMBL29967356 0.81 ALOX5 (0.53) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL810744 0.81 ALOX5 (0.53) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL14960049 0.80 MAPT (0.51) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL31043299 0.80 MAPT (0.54) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL2049691 0.79 HPGD (0.41) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL810748 0.78 MAPT (0.53) MAPTPTGS2MEN1KMT2AALOX5
SCHEMBL31674421 0.78 MAPT (0.49) MAPTPTGS2MEN1KMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9982129-B2 Polycarbonate resin composition, and optical material and optical lens each manufactured using same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-05-29 US disclosed
US-20170051146-A1 POLYCARBONATE RESIN COMPOSITION, AND OPTICAL MATERIAL AND OPTICAL LENS EACH MANUFACTURED USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-02-23 US disclosed
US-9360593-B2 Polycarbonate resin, production method therefor, and optical molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-06-07 US disclosed
US-20150285954-A1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-10-08 US disclosed