SCHEMBL17148019

SCHEMBL17148019

COCCOc1ccc2ccccc2c1-c1c(OCCOC(C)=O)ccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
PTGS2 P35354 4/20 0.43
MMP3 P08254 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
THRB P10828 1/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
ALOX5 P09917 1/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25667145 0.89 KDM4E (0.39) MAPTPTGS2MMP3KDM4EALDH1A1
SCHEMBL25913703 0.87 MAPT (0.45) MAPTPTGS2MMP3KDM4EALDH1A1
SCHEMBL22416800 0.83 MAPT (0.53) MAPTPTGS2MMP3KDM4EALDH1A1
SCHEMBL17148017 0.82 MAPT (0.49) MAPTPTGS2HPGDALOX5
SCHEMBL26935165 0.82 MMP3 (0.39) MAPTPTGS2MMP3KDM4EALDH1A1
SCHEMBL10398142 0.81 MAPT (0.44) MAPTPTGS2MMP3KDM4EALDH1A1
SCHEMBL1902160 0.80 KDM4E (0.64) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL13210145 0.79 NCEH1 (0.56) MMP3KDM4EALDH1A1HPGDTSHR
SCHEMBL14069123 0.77 THRB (0.60) MAPTPTGS2KDM4EALDH1A1HPGD
SCHEMBL29745802 0.77 THRB (0.60) MAPTPTGS2KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192950-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LIMITED (JP) 2023-06-22 US disclosed
EP-3750939-B1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY MITSUBISHI GAS CHEMICAL CO (JP) 2023-05-24 EP disclosed
US-9360593-B2 Polycarbonate resin, production method therefor, and optical molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-06-07 US disclosed
US-20150285954-A1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-10-08 US disclosed