Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967356 | 1.00 | ALOX5 (0.53) | ALOX5MAPTMEN1KMT2ACETP | |
| SCHEMBL1446528 | 0.91 | MAPT (0.63) | ALOX5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL29820187 | 0.91 | MAPT (0.63) | ALOX5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL26736125 | 0.84 | ALOX5 (0.55) | ALOX5MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31043299 | 0.83 | MAPT (0.54) | ALOX5MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL6563131 | 0.82 | MAPT (0.79) | ALOX5MAPTMEN1KMT2ACETP | |
| SCHEMBL30785795 | 0.82 | MAPT (0.79) | ALOX5MAPTMEN1KMT2ACETP | |
| SCHEMBL810748 | 0.82 | MAPT (0.53) | ALOX5MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17148017 | 0.81 | MAPT (0.49) | ALOX5MAPTMEN1KMT2APTGS2 | |
| SCHEMBL30560666 | 0.81 | MAPT (0.46) | ALOX5MAPTCETPCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486815-A | Chiral fluorescent probe and preparation method and application thereof | 中国药科大学 | 2024-02-02 | — | — | CN | claimed |
| CN-113233966-B | Chiral fluorescence sensor, preparation method thereof and application thereof in chiral amino acid recognition | 中国药科大学 | 2022-03-08 | — | — | CN | claimed |
| CN-113233966-A | Chiral fluorescence sensor, preparation method thereof and application thereof in chiral amino acid recognition | 中国药科大学 | 2021-08-10 | — | — | CN | claimed |
| EP-0915073-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | EP | claimed |
| CN-117486815-A | Chiral fluorescent probe and preparation method and application thereof | 中国药科大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-110790645-A | Amphipathic binaphthyl derivative containing dihydroxy, preparation method thereof and application of derivative in distinguishing chiral cyclohexanediamine gas | 陕西师范大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-107814729-A | A kind of chiral aromatic amine compounds and preparation method thereof | 中国科学技术大学 | 2018-03-20 | — | — | CN | disclosed |
| US-7928257-B2 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7897819-B2 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7897819-B2 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7754899-B2 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-07-13 | — | — | US | disclosed |
| US-7754899-B2 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20100113835-A1 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100113815-A1 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100113835-A1 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20080081916-A1 | Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-03 | — | — | US | disclosed |
| US-20080081916-A1 | Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-0915073-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6103914-A | Method of producing optically active material of tricyclic compound | TORAY INDUSTRIES, INC. (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0915073-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMERS OF TRICYCLIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081916-A1 | Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method | INTS9, RAD54L, CD99 | ALOX5 3545/4885MAPT 3728/4885MEN1 983/4885 |
| US-20100113815-A1 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | RAD54L, ATXN2L, CD99 | ALOX5 3724/4885MAPT 3282/4885MEN1 1185/4885 |
| US-20100113835-A1 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | RAD54L, ATXN2L, CD99 | ALOX5 3724/4885MAPT 3282/4885MEN1 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.