Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646245 | 0.70 | CDK4 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL15765152 | 0.70 | CDK4 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL15088369 | 0.69 | ALDH1A1 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL17191417 | 0.69 | KDM4E (0.54) | KDM4EALDH1A1 | |
| SCHEMBL15493837 | 0.68 | — | — | |
| SCHEMBL15132861 | 0.68 | TRPA1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL18898023 | 0.67 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL9805298 | 0.67 | ALDH1A1 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL16131275 | 0.67 | ALDH1A1 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL19019141 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678302-B1 | PROCESS TO OBTAIN A TRIFLUOROMETHYLATING COMPOSITION | FUNDACIÓ INST CATALÀ D INVESTIGACIÓ QUÍMICA (ES) | 2016-08-17 | — | — | EP | disclosed |
| US-20150284341-A1 | FLUOROALKYL-SUBSTITUTED DERIVATIVES OF PYRIDINE, PYRIMIDINE, AND PYRAZINE | CATYLIX INC (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284341-A1 | FLUOROALKYL-SUBSTITUTED DERIVATIVES OF PYRIDINE, PYRIMIDINE, AND PYRAZINE | PFAS, AFF2, AFF4 | KDM4E 2862/4885ALDH1A1 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.