Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998810 | 0.93 | DGKA (0.52) | DGKAMAPTLMNADNM1EPHX2 | |
| SCHEMBL3028188 | 0.86 | DGKA (0.46) | DGKAMAPTLMNADNM1EPHX2 | |
| SCHEMBL2964605 | 0.85 | ALDH1A1 (0.42) | DGKAMAPTLMNAEPHX2ALDH1A1 | |
| SCHEMBL3882499 | 0.84 | DGKA (0.61) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL755078 | 0.84 | DGKA (0.50) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL17908823 | 0.82 | DGKA (0.54) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL17909685 | 0.82 | DGKA (0.54) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL17908637 | 0.82 | DGKA (0.54) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL17909366 | 0.82 | DGKA (0.54) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL17908885 | 0.82 | DGKA (0.54) | DGKAMAPTLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220683-A1 | SEMI-SOLID DELIVERY SYSTEMS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-08-04 | — | — | US | disclosed |
| US-20150283244-A1 | SEMI-SOLID DELIVERY SYSTEMS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220683-A1 | SEMI-SOLID DELIVERY SYSTEMS | ACSS2, HDAC1, PAICS | DGKA 3693/4885MAPT 2148/4885LMNA 1422/4885 |
| US-20150283244-A1 | SEMI-SOLID DELIVERY SYSTEMS | REL, SSB, MSR1 | DGKA 4441/4885MAPT 3601/4885LMNA 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.