SCHEMBL17149271

SCHEMBL17149271

COC(=O)c1sc2ccc(C)cc2c1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
GLA P06280 2/20 0.43
GAA P10253 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALOX15 P16050 1/20 0.43
ATM Q13315 1/20 0.43
NR4A2 P43354 2/20 0.40
CMA1 P23946 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPK14 Q16539 2/20 0.38
RAF1 P04049 1/20 0.38
BACE1 P56817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18791342 0.89 BCL2L1 (0.47) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL15697577 0.86 CFTR (0.47) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL160072 0.85 CMA1 (0.44) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL2610282 0.84 MCL1 (0.50) ALDH1A1BCL2L1MCL1
SCHEMBL903483 0.83 BCL2L1 (0.42) LMNAALDH1A1KDM4EMAPTGAA
SCHEMBL15697557 0.81 LMNA (0.63) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL17149269 0.81 LMNA (0.50) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL28174494 0.80 MAPK1 (0.65) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL15471997 0.80 BCL2L1 (0.55) LMNAMAPK1ALDH1A1KDM4EMAPT
SCHEMBL17149272 0.80 MAPK1 (0.49) LMNAMAPK1ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B LMNA 4787/4885MAPK1 1018/4885ALDH1A1 775/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 LMNA 4736/4885MAPK1 1907/4885ALDH1A1 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.