Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.76 |
| ▸ | GFER | P55789 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714644 | 0.81 | PKM (0.61) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL11508895 | 0.78 | GAA (0.82) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL2769068 | 0.78 | ALDH1A1 (0.71) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL5255516 | 0.77 | GAA (0.80) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL2961007 | 0.75 | SMN1; SMN2 (0.80) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL15658838 | 0.74 | LMNA (0.61) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL11507203 | 0.74 | GAA (0.74) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL9312346 | 0.74 | GAA (0.74) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL5747349 | 0.74 | GAA (0.69) | GAAGFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL1374567 | 0.72 | HDAC3 (0.80) | GAAGFERKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |