Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087536 | 0.89 | PARP15 (0.70) | PARP15PARP10PARP2ACACBL3MBTL1 | |
| SCHEMBL12420708 | 0.86 | PARP15 (0.58) | PARP15PARP10PARP2ACACBMCHR1 | |
| SCHEMBL4117982 | 0.86 | PARP10 (0.71) | PARP15PARP10PARP2L3MBTL1ALDH1A1 | |
| SCHEMBL6958286 | 0.84 | PARP10 (0.72) | PARP15PARP10PARP2L3MBTL1ALDH1A1 | |
| SCHEMBL28866432 | 0.84 | L3MBTL1 (0.54) | PARP15PARP10PARP2L3MBTL1ALDH1A1 | |
| SCHEMBL22386747 | 0.84 | PARP15 (0.52) | PARP15PARP10PARP2ACACBMCHR1 | |
| SCHEMBL17150425 | 0.82 | PARP15 (0.54) | PARP15PARP10PARP2ACACBGAA | |
| SCHEMBL7733823 | 0.82 | PARP15 (0.66) | PARP15PARP10PARP2L3MBTL1ALDH1A1 | |
| SCHEMBL7737448 | 0.82 | PARP10 (0.66) | PARP15PARP10PARP2L3MBTL1ALDH1A1 | |
| SCHEMBL13096941 | 0.80 | ALDH1A1 (0.43) | PARP15PARP10PARP2ACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144900-A1 | SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2018-08-09 | — | — | WO | disclosed |
| WO-2015150366-A1 | CYCLICALLY SUBSTITUTED PHENOL ETHER DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |