SCHEMBL17152142

SCHEMBL17152142

CCCCCCCCCCCCCCCCCCNC(=O)C=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.60
APP P05067 1/20 0.60
HTR1A P08908 2/20 0.59
HTR2C P28335 2/20 0.59
HTR2A P28223 1/20 0.59
SLC6A4 P31645 1/20 0.59
HTR7 P34969 1/20 0.59
HTR6 P50406 1/20 0.59
GABBR2 O75899 1/20 0.51
GABBR1 Q9UBS5 1/20 0.51
MAOA P21397 11/20 0.51
ACHE P22303 11/20 0.51
MAOB P27338 11/20 0.51
BCHE P06276 1/20 0.51
GAA P10253 1/20 0.50
NR5A2 O00482 1/20 0.47
NR5A1 Q13285 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7668323 0.95 GABBR2 (0.56) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL2119406 0.95 GABBR2 (0.56) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL17152151 0.93 EGFR (0.55) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL28529805 0.86 GABBR2 (0.52) APPGABBR2GABBR1MAOAACHE
SCHEMBL19359019 0.84 APP (0.73) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL19369316 0.84 APP (0.73) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL6022580 0.84 HTR1A (0.53) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL6022842 0.84 HTR1A (0.53) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL6022576 0.84 HTR1A (0.53) EGFRAPPHTR1AHTR2CHTR2A
SCHEMBL6022838 0.84 HTR1A (0.53) EGFRAPPHTR1AHTR2CHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103849006-B Stabilizer with bifunctional structure and composition thereof 奕益实业有限公司 2016-06-22 CN disclosed
US-20150315360-A1 DIFUNCTIONAL WEATER-RESISTANT STABILIZER AND POLYMER COMPOSITION CONTAINING THE SAME FDC LEES CHEMICAL INDUSTRY CO., LTD. (TW) 2015-11-05 US disclosed
US-9156964-B1 Difunctional weather-resistant stabilizer and polymer composition containing the same FDC LEES CHEMICAL INDUSTRY CO., LTD. (TW) 2015-10-13 US disclosed