Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053655 | 0.85 | ALDH1A1 (0.36) | DPP7HPGD | |
| SCHEMBL17152299 | 0.82 | HTR1A (0.40) | PHGDHMGLL | |
| SCHEMBL17152647 | 0.78 | PIK3CD (0.51) | — | |
| SCHEMBL17152625 | 0.76 | HRH3 (0.33) | DPP4DPP7 | |
| SCHEMBL14152389 | 0.75 | DPP4 (0.34) | DPP4 | |
| SCHEMBL17152366 | 0.75 | BTK (0.34) | — | |
| SCHEMBL17152545 | 0.75 | POLB (0.39) | HPGDPHGDHMGLL | |
| SCHEMBL15203457 | 0.75 | DPP4 (0.35) | DPP4DPP8DPP9 | |
| SCHEMBL17152479 | 0.74 | DPP4 (0.47) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL17152317 | 0.74 | ENPP2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |