Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750112 | 0.82 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL17152522 | 0.82 | MEN1 (0.52) | ALDH1A1RXFP1KDM4EMEN1KMT2A | |
| SCHEMBL17152403 | 0.82 | MEN1 (0.52) | ALDH1A1RXFP1KDM4EMEN1KMT2A | |
| SCHEMBL6512150 | 0.82 | MEN1 (0.52) | ALDH1A1RXFP1KDM4EMEN1KMT2A | |
| SCHEMBL17152615 | 0.81 | MEN1 (0.51) | ALDH1A1RXFP1KDM4EMEN1KMT2A | |
| SCHEMBL18420823 | 0.77 | ACKR3 (0.42) | ALDH1A1ARG1ARG2RXFP1KDM4E | |
| SCHEMBL17152568 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ARG1ARG2RXFP1KDM4E | |
| SCHEMBL18420992 | 0.75 | ARG1 (0.45) | ARG1ARG2SLC7A5 | |
| SCHEMBL19478684 | 0.74 | PLK1 (0.33) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL19478688 | 0.74 | PLK1 (0.33) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |