Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29864695 | 1.00 | MEN1 (0.45) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL2177285 | 0.80 | SNCA (0.50) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL28790103 | 0.80 | TNNI3 (0.45) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL30674368 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL5052239 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL714638 | 0.79 | TTR (0.51) | GAAMAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL6305294 | 0.79 | MPL (0.45) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL21037491 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL9338089 | 0.76 | CTRB1 (0.44) | GAAKDM4EHCRTR1HKDC1CTRB1 | |
| SCHEMBL10354309 | 0.75 | CTRB1 (0.47) | ALDH1A1HCRTR1HKDC1CTRB1G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021800-B1 | DETERMINATION OF CHANGES IN CONCENTRATION | JACOBS UNIVERSITY BREMEN GMBH (DE) | 2011-07-20 | — | — | EP | disclosed |