Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CDA | P32320 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 3/20 | 0.36 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173369 | 1.00 | TYMP (0.40) | TYMPMAPTCDAPYGMTK2 | |
| SCHEMBL17157237 | 1.00 | TYMP (0.40) | TYMPMAPTCDAPYGMTK2 | |
| SCHEMBL17177264 | 1.00 | TYMP (0.40) | TYMPMAPTCDAPYGMTK2 | |
| SCHEMBL17157236 | 1.00 | TYMP (0.40) | TYMPMAPTCDAPYGMTK2 | |
| SCHEMBL19901613 | 1.00 | TYMP (0.40) | TYMPMAPTCDAPYGMTK2 | |
| SCHEMBL22179139 | 1.00 | TYMP (0.40) | TYMPMAPTCDAPYGMTK2 | |
| SCHEMBL17177287 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL17157274 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL17173379 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL19901627 | 0.86 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900679-B1 | 5-FLUOROURIDINE DERIVATIVES | BRAUN MELSUNGEN AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-9902752-B2 | 5-fluorouracil derivatives | B. BRAUN MELSUNGEN AG (DE) | 2018-02-27 | — | — | US | disclosed |
| US-20150291649-A1 | 5-Fluorouracil Derivatives | B. BRAUN MELSUNGEN AG (DE) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291649-A1 | 5-Fluorouracil Derivatives | DPYD, FAU, DHFR | TYMP 7/4885MAPT 3996/4885CDA 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.