SCHEMBL17157262

SCHEMBL17157262

Cc1ccc2c(N)nc3ccccc3c2n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 4/20 0.49
TLR8 Q9NR97 3/20 0.49
NCF1 P14598 1/20 0.49
DCPS Q96C86 1/20 0.48
CYP1A2 P05177 4/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 3/20 0.46
NUDT1 P36639 1/20 0.46
ADORA3 P0DMS8 3/20 0.46
ADORA2A P29274 2/20 0.46
ADORA1 P30542 1/20 0.46
CYP1A1 P04798 1/20 0.45
CYP1B1 Q16678 1/20 0.45
BACE1 P56817 1/20 0.44
HTR3A P46098 1/20 0.44
HRH4 Q9H3N8 1/20 0.44
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008185 0.87 TLR7 (0.54) TLR7TLR8NCF1DCPSCYP1A2
SCHEMBL17532743 0.81 GPR3 (0.59) NCF1CYP1A2ALDH1A1HPGDHSD17B10
SCHEMBL3786280 0.80 CCR1 (0.52) CYP1A2ALDH1A1ADORA1KDM4ETDP1
SCHEMBL17157259 0.79 ADORA2A (0.44) TLR7TLR8NCF1DCPSCYP1A2
SCHEMBL30608515 0.78 CCR1 (0.50) CYP1A2ALDH1A1ADORA1KDM4ETDP1
SCHEMBL17157263 0.78 NR4A2 (0.57) TLR7ADORA1HTR3AHRH4CHRM1
SCHEMBL17157221 0.77 HTR3A (0.49) ALDH1A1ADORA3ADORA2AHTR3AHRH4
SCHEMBL17157215 0.76 NR4A2 (0.45) TLR7ACHEMAPT
SCHEMBL6267429 0.76 CCR1 (0.63) CYP1A2ADORA2AADORA1GAAMAPT
SCHEMBL10372511 0.74 CYP1A2 (0.54) NCF1CYP1A2ALDH1A1NQO2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563335-A Organic electroluminescent material and device 环球展览公司 2021-10-29 CN disclosed
CN-104974155-B Organic electroluminescent material and device 环球展览公司 2021-08-10 CN disclosed
US-9905785-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-9905785-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-9905785-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-20150295189-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-10-15 US disclosed
US-20150295189-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-10-15 US disclosed
US-20150295189-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-10-15 US disclosed