SCHEMBL3786280

SCHEMBL3786280

Cc1ccc2c3ccccc3c3ccccc3c2n1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.52
RAB9A P51151 1/20 0.52
CCR5 P51681 1/20 0.52
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
OPRK1 P41145 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 2/20 0.44
METAP2 P50579 1/20 0.43
GPR3 P46089 1/20 0.43
HPRT1 P00492 1/20 0.42
KDM4E B2RXH2 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.39
CCR8 P51685 1/20 0.39
ADORA1 P30542 1/20 0.38
CTSB P07858 1/20 0.38
CTSH P09668 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608515 0.98 CCR1 (0.50) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL6267429 0.89 CCR1 (0.63) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL20313299 0.88 MAOA (0.50) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL21959272 0.85 L3MBTL1 (0.57) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL16231063 0.84 L3MBTL1 (0.42) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL9611713 0.83 L3MBTL1 (0.55) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL20313291 0.82 CCR1 (0.44) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL17157262 0.80 TLR7 (0.49) RAB9AMAPTALDH1A1CYP1A2KDM4E
SCHEMBL17532743 0.79 GPR3 (0.59) CCR1RAB9ACCR5MAPTL3MBTL1
SCHEMBL9976736 0.79 L3MBTL1 (0.46) CCR1RAB9ACCR5MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138254-A1 HETEROCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ELEMENT 上海八亿时空先进材料有限公司 2023-07-27 WO disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20210028376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 US disclosed
US-10403825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
US-10355222-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-07-16 US disclosed
US-10177316-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-01-08 US disclosed
US-9761814-B2 Organic light-emitting materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-09-12 US disclosed
US-9761814-B2 Organic light-emitting materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-09-12 US disclosed
US-9537106-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-01-03 US disclosed
US-20140332758-A1 DONOR-ACCEPTOR COMPOUNDS WITH NITROGEN CONTAINING POLYAROMATICS AS THE ACCEPTOR UNIVERSAL DISPLAY CORPORATION (US) 2014-11-13 US disclosed
US-8822042-B2 Luminescent cyclometallated iridium(III) complexes having acetylide ligands THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2014-09-02 US disclosed
US-8753756-B2 Green phosphorescent iridium complexes, fabrication method thereof and organic light-emitting diodes comprising the same Cheng, Chien-Hong (TW) 2014-06-17 US disclosed
US-8753756-B2 Green phosphorescent iridium complexes, fabrication method thereof and organic light-emitting diodes comprising the same Cheng, Chien-Hong (TW) 2014-06-17 US disclosed
US-8753756-B2 Green phosphorescent iridium complexes, fabrication method thereof and organic light-emitting diodes comprising the same Cheng, Chien-Hong (TW) 2014-06-17 US disclosed
US-20140145151-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed
US-20120007061-A1 Luminescent Cyclometallated Iridium(III) Complexes Having Acetylide Ligands THE UNIVERSITY OF SOUTHERN CALIFORNIA 2012-01-12 US disclosed
US-20100327736-A1 GREEN PHOSPHORESCENT IRIDIUM COMPLEXES, FABRICATION METHOD THEREOF AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME Cheng, Chien-Hong (TW) 2010-12-30 US disclosed
US-20100327736-A1 GREEN PHOSPHORESCENT IRIDIUM COMPLEXES, FABRICATION METHOD THEREOF AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME Cheng, Chien-Hong (TW) 2010-12-30 US disclosed
US-20100327736-A1 GREEN PHOSPHORESCENT IRIDIUM COMPLEXES, FABRICATION METHOD THEREOF AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME Cheng, Chien-Hong (TW) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403825-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP CCR1 3154/4885RAB9A 2555/4885CCR5 1782/4885
US-20100327736-A1 GREEN PHOSPHORESCENT IRIDIUM COMPLEXES, FABRICATION METHOD THEREOF AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME IK, INTS6, NR2E3 CCR1 1024/4885RAB9A 2121/4885CCR5 325/4885
US-10355222-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OPRD1 CCR1 4168/4885RAB9A 2597/4885CCR5 2247/4885
US-20120007061-A1 Luminescent Cyclometallated Iridium(III) Complexes Having Acetylide Ligands ACACA, SIRT3, ICOSLG CCR1 2328/4885RAB9A 2574/4885CCR5 1858/4885
US-10177316-B2 Organic electroluminescent materials and devices OSBP, OSBPL3, OSBP2 CCR1 4102/4885RAB9A 1331/4885CCR5 2719/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP CCR1 3154/4885RAB9A 2555/4885CCR5 1782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.