Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.39 |
| ▸ | MTOR | P42345 | 6/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | ICOSLG | O75144 | 1/20 | 0.33 |
| ▸ | ICOS | Q9Y6W8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17157430 | 0.82 | GPBAR1 (0.43) | PIK3CAMTORGPBAR1HPGDMLYCD | |
| SCHEMBL14732232 | 0.82 | PIK3CA (0.36) | PIK3CAMTORGPBAR1ICAM1SELE | |
| SCHEMBL22791669 | 0.75 | ALDH1A1 (0.43) | ICOSLGICOSKDM4EALDH1A1ABL1 | |
| SCHEMBL2507311 | 0.74 | HCAR2 (0.46) | PIK3CAMTORICAM1SELEHPGD | |
| SCHEMBL30041415 | 0.74 | OPRK1 (0.37) | PIK3CAMTORALDH1A1 | |
| SCHEMBL21591708 | 0.74 | OPRK1 (0.37) | PIK3CAMTORALDH1A1 | |
| SCHEMBL24556486 | 0.74 | HPGD (0.31) | GPBAR1HPGDKDM4EALDH1A1CYP1A2 | |
| SCHEMBL307472 | 0.73 | P2RX7 (0.50) | KDM4EALDH1A1CYP3A4ALOX15TRPM8 | |
| SCHEMBL17157497 | 0.73 | SIRT3 (0.54) | GPBAR1ICAM1SELEMLYCDKDM4E | |
| SCHEMBL8578654 | 0.72 | SMN1; SMN2 (0.45) | KDM4EALDH1A1CYP1A2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180298038-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-10-18 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | GPX1, POR, MGAM | PIK3CA 4075/4885MTOR 3799/4885GPBAR1 1362/4885 |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | PIK3CA 4075/4885MTOR 3799/4885GPBAR1 1362/4885 |
| US-20180298038-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | PIK3CA 4075/4885MTOR 3799/4885GPBAR1 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.