Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17157370 | 0.87 | ABL1 (0.49) | ABL1NPC1RAB9AL3MBTL1 | |
| SCHEMBL17157523 | 0.84 | ABL1 (0.44) | ABL1SCN10ATEK | |
| SCHEMBL17172160 | 0.82 | RXFP1 (0.47) | — | |
| SCHEMBL5123658 | 0.80 | AURKA (0.51) | NPC1RAB9ASCN10ATEKAURKA | |
| SCHEMBL12700407 | 0.80 | NPC1 (0.56) | ABL1NPC1RAB9A | |
| SCHEMBL17157457 | 0.77 | MEN1 (0.46) | ABL1NPC1RAB9ASCN10ATEK | |
| SCHEMBL8103595 | 0.75 | ABL1 (0.54) | ABL1 | |
| SCHEMBL12614281 | 0.74 | VNN1 (0.52) | ABL1NPC1RAB9ASCN10AAURKA | |
| SCHEMBL17157312 | 0.74 | LIPE (0.45) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9288749 | 0.71 | ABL1 (0.51) | ABL1NPC1RAB9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180298038-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-10-18 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| EP-3131399-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015160665-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160665-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | GPX1, POR, MGAM | ABL1 474/4885NPC1 799/4885RAB9A 2842/4885 |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | ABL1 474/4885NPC1 799/4885RAB9A 2842/4885 |
| US-20180298038-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | ABL1 474/4885NPC1 799/4885RAB9A 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.