Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.89 |
| ▸ | MMP3 | P08254 | 2/20 | 0.70 |
| ▸ | MMP9 | P14780 | 2/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.66 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.62 |
| ▸ | XDH | P47989 | 2/20 | 0.62 |
| ▸ | IPMK | Q8NFU5 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17166286 | 0.94 | APP (1.00) | APPMMP3MMP9CYP1B1CYP1A1 | |
| SCHEMBL17166016 | 0.89 | APP (0.70) | APPMMP3MMP9CYP1B1CYP1A1 | |
| SCHEMBL7637240 | 0.84 | APP (0.81) | APPMMP3MMP9CYP1B1CYP1A1 | |
| SCHEMBL13672774 | 0.83 | APP (0.80) | APPMMP3MMP9MEN1KMT2A | |
| Sotetsuflavone SCHEMBL30646165 | 0.83 | APP (0.80) | APPMMP3MMP9CYP1B1CYP1A1 | |
| Sotetsuflavone SCHEMBL4467051 | 0.83 | APP (0.80) | APPMMP3MMP9CYP1B1CYP1A1 | |
| SCHEMBL30766312 | 0.82 | APP (0.79) | APPMMP3MMP9CYP1B1CYP1A1 | |
| 7'',4'''-Dimethylamentoflavone SCHEMBL27350631 | 0.82 | APP (0.72) | APPMMP3MMP9CYP1B1CYP1A1 | |
| 7'',4'''-Dimethylamentoflavone SCHEMBL30646161 | 0.82 | APP (0.72) | APPMMP3MMP9CYP1B1CYP1A1 | |
| SCHEMBL17166015 | 0.82 | MEN1 (0.74) | APPMMP3MMP9CYP1B1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155792-B2 | RecA inhibitors with antibiotic activity, compositions and methods of use | TRUSTEES OF BOSTON UNIVERSITY (US) | 2015-10-13 | — | — | US | disclosed |