Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.66 |
| ▸ | FLT3 | P36888 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485651 | 0.94 | MAPT (0.72) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| Hinokiflavone SCHEMBL4649967 | 0.85 | MAPT (0.66) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| Hinokiflavone SCHEMBL617272 | 0.82 | KMT2A (0.70) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| Hinokiflavone SCHEMBL30063752 | 0.82 | KMT2A (0.70) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| SCHEMBL12636897 | 0.82 | CYP1B1 (0.81) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| SCHEMBL17166013 | 0.82 | APP (0.89) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| Acacetin SCHEMBL107712 | 0.81 | CYP1B1 (1.00) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| Acacetin SCHEMBL29387049 | 0.81 | CYP1B1 (1.00) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| SCHEMBL30192733 | 0.81 | CYP1B1 (0.80) | CYP1B1FLT3MAPTCYP1A1CYP1A2 | |
| Salvigenin SCHEMBL1427018 | 0.80 | FLT3 (1.00) | CYP1B1FLT3MAPTCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155792-B2 | RecA inhibitors with antibiotic activity, compositions and methods of use | TRUSTEES OF BOSTON UNIVERSITY (US) | 2015-10-13 | — | — | US | disclosed |