Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.64 |
| ▸ | GABRD | O14764 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485651 | 0.91 | MAPT (0.72) | MAPTPOLBKDM4EADORA3FLT3 | |
| Hinokiflavone SCHEMBL617272 | 0.88 | KMT2A (0.70) | MAPTPOLBKDM4EADORA3FLT3 | |
| Hinokiflavone SCHEMBL30063752 | 0.88 | KMT2A (0.70) | MAPTPOLBKDM4EADORA3FLT3 | |
| SCHEMBL17166017 | 0.85 | CYP1B1 (0.66) | MAPTPOLBKDM4EADORA3FLT3 | |
| SCHEMBL4918477 | 0.82 | MAOA (0.83) | MAPTPOLBKDM4EADORA3FLT3 | |
| Cirsimaritin SCHEMBL29459674 | 0.81 | POLB (1.00) | MAPTPOLBKDM4EADORA3FLT3 | |
| Cirsimaritin SCHEMBL1663486 | 0.81 | POLB (1.00) | MAPTPOLBKDM4EADORA3FLT3 | |
| SCHEMBL735537 | 0.81 | MAPT (0.85) | MAPTPOLBKDM4EADORA3FLT3 | |
| SCHEMBL13485654 | 0.81 | QPCT (0.80) | MAPTPOLBKDM4EFLT3MEN1 | |
| SCHEMBL29574485 | 0.80 | MAOA (0.79) | MAPTPOLBKDM4EFLT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |