SCHEMBL17167174

SCHEMBL17167174

NCCOCCOCCOCCC(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TDP1 Q9NUW8 2/20 0.49
KMT2A Q03164 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
IDO1 P14902 1/20 0.44
NOTUM Q6P988 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14762052 1.00 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL16620755 1.00 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL21814470 1.00 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL25933078 0.98 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL29467614 0.96 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL24983131 0.89 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL30426434 0.88 TDP1 (0.51) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL31235810 0.88 SMN1; SMN2 (0.56) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL20107370 0.88 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2
SCHEMBL21713242 0.87 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 US disclosed
WO-2025111431-A1 ANTI-CD7 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF LES LABORATOIRES SERVIER (FR) 2025-05-30 WO disclosed
EP-4525928-A1 ANTIBODY DRUG CONJUGATES Novartis AG (CH) 2025-03-26 EP disclosed
EP-4525927-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF Novartis AG (CH) 2025-03-26 EP disclosed
WO-2023223097-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2023-11-23 WO disclosed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 WO disclosed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 WO disclosed
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-01-12 US disclosed
US-20220023438-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES PIERRE FABRE MEDICAMENT (FR) 2022-01-27 US disclosed
WO-2020065408-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES PIERRE FABRE MEDICAMENT (FR) 2020-04-02 WO disclosed
US-9879041-B2 Saccharide dendritic cluster compounds as inhibitors of BACE-1 VICTORIA LINK LIMITED (NZ) 2018-01-30 US disclosed
US-9828341-B2 Dendritic core compounds VICTORIA LINK LIMITED (NZ) 2017-11-28 US disclosed
US-9828341-B2 Dendritic core compounds VICTORIA LINK LIMITED (NZ) 2017-11-28 US disclosed
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 UNIVERSITY OF LIVERPOOL (GB) 2017-06-01 US disclosed
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 UNIVERSITY OF LIVERPOOL (GB) 2017-06-01 US disclosed
US-20150291522-A1 DENDRITIC CORE COMPOUNDS CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) 2015-10-15 US disclosed
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 US disclosed
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 US disclosed
US-20150291522-A1 DENDRITIC CORE COMPOUNDS CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220023438-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES CSGALNACT1, CD44, IGLV6-57 ALDH1A1 1115/4885MAPK1 2905/4885L3MBTL1 4254/4885
US-20150291522-A1 DENDRITIC CORE COMPOUNDS FLOT1, DBN1, DCTN3 ALDH1A1 3695/4885MAPK1 4424/4885L3MBTL1 4842/4885
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP ALDH1A1 2404/4885MAPK1 2451/4885L3MBTL1 3839/4885
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 ALDH1A1 4315/4885MAPK1 3051/4885L3MBTL1 1429/4885
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP DAO, DDO, DCLRE1A ALDH1A1 60/4885MAPK1 4194/4885L3MBTL1 1197/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 ALDH1A1 3069/4885MAPK1 2112/4885L3MBTL1 264/4885
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP ALDH1A1 2404/4885MAPK1 2451/4885L3MBTL1 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.