SCHEMBL17167461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20127307	0.93	TDP1 (0.41)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL16543091	0.92	ABCG2 (0.54)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL22260605	0.91	ABCG2 (0.48)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL22155571	0.91	ABCG2 (0.41)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL20127292	0.90	TDP1 (0.44)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL20706685	0.90	KDM4E (0.47)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL22155062	0.89	ABCG2 (0.42)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL20906810	0.89	ABCG2 (0.44)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL24362942	0.88	CYP1A1 (0.41)	TDP1L3MBTL1ABCG2PAX8CYP1A1
	SCHEMBL22155076	0.88	ABCG2 (0.46)	TDP1L3MBTL1ABCG2PAX8CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.