Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 15/20 | 0.62 |
| ▸ | ATP4B | P51164 | 15/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.62 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | FASN | P49327 | 1/20 | 0.62 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.62 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | ATP1A1 | P05023 | 9/20 | 0.53 |
| ▸ | ATP1B1 | P05026 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pantoprazole SCHEMBL30777582 | 0.99 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL22198 | 0.99 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29463615 | 0.99 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL723548 | 0.99 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29466 | 0.99 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29530572 | 0.99 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL1994486 | 0.98 | ATP4A (0.62) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL3179782 | 0.98 | ATP4A (0.62) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL289961 | 0.98 | ATP4A (0.62) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29001005 | 0.98 | ATP4A (0.62) | ATP4AATP4BCYP2C9CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754108-B2 | Freeze-dried pantoprazole preparation and pantoprazole injection | Takeda, GmbH (DE) | 2014-06-17 | — | — | US | claimed |
| EP-2316454-B9 | Dosage form containing pantoprazole as active ingredient | NYCOMED GMBH (DE) | 2013-01-02 | — | — | EP | claimed |
| EP-2316454-B1 | Dosage form containing pantoprazole as active ingredient | NYCOMED GMBH (DE) | 2012-09-26 | — | — | EP | claimed |
| EP-1746980-B1 | PHARMACEUTICAL DOSAGE FORM COMPRISING PELLETS AS WELL AS ITS MANUFACTURING PROCESS | NYCOMED GMBH (DE) | 2011-11-02 | — | — | EP | claimed |
| EP-1341524-B1 | PHARMACEUTICAL PREPARATION IN THE FORM OF A PASTE COMPRISING AN ACID-LABILE ACTIVE INGREDIENT | NYCOMED GMBH (DE) | 2011-10-19 | — | — | EP | claimed |
| US-7838027-B2 | multiparticulates have spheroid core of pantoprazole or an enantiomer or a salt thereof, a surfactant, a disintegrant, a sub coat which is comprised of hydroxypropyl methylcellulose and water, an enteric coat, a seal coat; less prone to adherence to the intestinal walls, nasogastric and gastromy tubes | WYETH LLC (US) | 2010-11-23 | — | — | US | claimed |
| CN-101524336-A | Dosage forms for oral administration of magnesium salt of pantoprazole | NICOMEDE CO LTD (DE) | 2009-09-09 | — | — | CN | claimed |
| US-20090220552-A1 | FORMULATIONS CONTAINING PANTOPRAZOLE FREE ACID AND ITS SALTS | COMBINO PHARM, S.L. (ES) | 2009-09-03 | — | — | US | claimed |
| US-20090208571-A1 | Dosage form containing pantoprazole as active ingredient | NYCOMED GMBH (DE) | 2009-08-20 | — | — | US | claimed |
| US-20090093522-A1 | Freeze-dried pantoprazole preparation and pantoprazole injection | NYCOMED GMBH | 2009-04-09 | — | — | US | claimed |
| US-20060240100-A1 | Dosage form containing pantoprazole as active ingredient | ALTANA PHARMA AG (DE) | 2006-10-26 | — | — | US | claimed |
| CN-1791406-A | Solid state forms of 5-(difluoro-methoxy)-2-((3,4-dimethoxy-2-pyridinyl)-methyl) sulfinyl]-1H-benzimidazole sodium aquo complexes | PLIVA ISTRAZIVACKI INST D O O (HR) | 2006-06-21 | — | — | CN | claimed |
| CN-1784227-A | Dosage form comprising pantoprazole as active ingredient | ALTANA PHARMA AG (DE) | 2006-06-07 | — | — | CN | claimed |
| CN-1250292-C | Pantoprazole freeze-dried preparation and pantoprazole injection | OTANNA MEDICINE AG (DE) | 2006-04-12 | — | — | CN | claimed |
| EP-1624869-A2 | DOSAGE FORM CONTAINING PANTOPRAZOLE AS ACTIVE INGREDIENT | ALTANA Pharma AG (DE) | 2006-02-15 | — | — | EP | claimed |
| WO-2005107721-A2 | PHARMACEUTICAL DOSAGE FORM COMPRISING PELLETS AS WELL AS ITS MANUFACTURING PROCESS | ALTANA PHARMA AG (DE) | 2005-11-17 | — | — | WO | claimed |
| WO-2005074932-A1 | THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | claimed |
| WO-2004098594-A2 | DOSAGE FORM CONTAINING PANTOPRAZOLE AS ACTIVE INGREDIENT | ALTANA PHARMA AG (DE) | 2004-11-18 | — | — | WO | claimed |
| US-20040220228-A1 | Freeze-dried pantoprazole preparation and pantoprazole injection | ALTANA PHARMA AG (DE) | 2004-11-04 | — | — | US | claimed |
| US-6780881-B2 | FREEZE- DRYING OF AN AQUEOUS SOLUTION OF PANTOPRAZOLE, A SALT THEREOF, SOLVATE OF PANTOPRAZOLE OR A SALT THEREOF, ETHYLENEDLAMINE TETRAACETIC ACID AND/OR A SUITABLE SALT THEREOF, AND SODIUM HYDROXIDE AND/OR SODIUM CARBONATE | ALTANA PHARMA AG (DE) | 2004-08-24 | — | — | US | claimed |