Pantoprazole

Pantoprazole

SCHEMBL289961

COc1ccnc(C[S@+]([O-])c2nc3ccc(OC(F)F)cc3[nH]2)c1OC.[NaH]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 15/20 0.62
ATP4B P51164 15/20 0.62
CYP2C9 P11712 3/20 0.62
CYP3A4 P08684 2/20 0.62
KDM4E B2RXH2 1/20 0.62
SLC22A2 O15244 1/20 0.62
DDAH1 O94760 1/20 0.62
ALDH1A1 P00352 1/20 0.62
LMNA P02545 1/20 0.62
ABCB1 P08183 1/20 0.62
MAPT P10636 1/20 0.62
HPGD P15428 1/20 0.62
ALOX15 P16050 1/20 0.62
ADRA1A P35348 1/20 0.62
FASN P49327 1/20 0.62
SLC47A2 Q86VL8 1/20 0.62
SLC47A1 Q96FL8 1/20 0.62
ABCG2 Q9UNQ0 1/20 0.62
ATP1A1 P05023 9/20 0.53
ATP1B1 P05026 9/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantoprazole SCHEMBL27634499 1.00 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL15540468 0.99 ATP4A (0.61) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL29463615 0.99 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL22198 0.99 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL723548 0.99 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL30777582 0.99 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL29530572 0.99 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL29466 0.99 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL1716779 0.98 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL3179782 0.98 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2628 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036684-A Preparation method of levorotatory pantoprazole sodium double-hemi-hydrate 杭州中美华东制药有限公司 2026-05-15 CN claimed
CN-119798220-A Preparation method of digestive drug intermediate 山东罗欣药业集团恒欣药业有限公司 2025-04-11 CN claimed
WO-2025045191-A1 PANTOPRAZOLE PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海云晟研新生物科技有限公司 2025-03-06 WO claimed
CN-119548499-A Pantoprazole pharmaceutical composition, preparation method and application thereof 上海云晟研新生物科技有限公司 2025-03-04 CN claimed
CN-119064364-A Pantoprazole sodium enteric capsule quality detection device 湖南明瑞制药股份有限公司 2024-12-03 CN claimed
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
US-20240238264-A1 INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF DISARM THERAPEUTICS, INC. 2024-07-18 US claimed
US-12005050-B2 Methods for preventing or treating H. pylori infection TENNOR THERAPEUTICS (SUZHOU) LIMITED (CN) 2024-06-11 US claimed
CN-221038207-U Pantoprazole sodium finished product sampling detection device for injection 济南兴鲁医药科技有限公司 2024-05-28 CN claimed
CN-117731664-B Preparation and application of tumor MRI diagnosis and treatment integrated nano probe for acidosis monitoring 山东第一医科大学(山东省医学科学院) 2024-05-10 CN claimed
US-6383510-B1 Suppository form comprising an acid-labile active compound BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2002-05-07 US claimed
US-20020025342-A1 Novel administration form comprising an acid-labile active compound BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH 2002-02-28 US claimed
US-6328993-B1 Oral administration form for an acid liable active proton pump inhibitor BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2001-12-11 US claimed
CN-1318065-A Novel salt form of pantoprazole BYK GUILDEN LOMBERG CHEMISCHE (DE) 2001-10-17 CN claimed
EP-1037607-A1 NOVEL SUPPOSITORY FORM COMPRISING AN ACID-LABILE ACTIVE COMPOUND Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 2000-09-27 EP claimed
EP-1037634-A1 NOVEL ADMINISTRATION FORM COMPRISING AN ACID-LABILE ACTIVE COMPOUND Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 2000-09-27 EP claimed
CN-1235018-A Pantoprazole sodium freeze-dried powder injection and preparation method thereof DONGYU PHARMACEUTICAL CO LTD S (CN) 1999-11-17 CN claimed
WO-1999029320-A1 NOVEL ADMINISTRATION FORM COMPRISING AN ACID-LABILE ACTIVE COMPOUND BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1999-06-17 WO claimed
WO-1999029299-A1 NOVEL SUPPOSITORY FORM COMPRISING AN ACID-LABILE ACTIVE COMPOUND BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1999-06-17 WO claimed
CN-1037932-C Method for preparing oral tablet and pill dosage form capable of tolerating gastric juice BYR GULDEN LOMBERG CHEMISCHE G (DE) 1998-04-08 CN claimed