Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356564 | 0.80 | MBOAT4 (0.40) | MBOAT4CLK4CCNCCDK8NPY5R | |
| SCHEMBL3242600 | 0.80 | CYP1A2 (0.44) | MBOAT4CLK4CCNCCDK8NPY5R | |
| SCHEMBL30607265 | 0.80 | MBOAT4 (0.40) | MBOAT4CLK4CCNCCDK8EGLN2 | |
| SCHEMBL14546705 | 0.80 | MBOAT4 (0.40) | MBOAT4CLK4CCNCCDK8NPY5R | |
| SCHEMBL7666624 | 0.80 | MBOAT4 (0.40) | MBOAT4CLK4CCNCCDK8NPY5R | |
| SCHEMBL29478779 | 0.80 | NOTUM (0.43) | MBOAT4CLK4CCNCCDK8NPY5R | |
| SCHEMBL16532586 | 0.80 | MBOAT4 (0.43) | MBOAT4CLK4CCNCCDK8VNN1 | |
| SCHEMBL481078 | 0.80 | NOTUM (0.43) | MBOAT4CLK4CCNCCDK8NPY5R | |
| SCHEMBL18078827 | 0.80 | MBOAT4 (0.40) | MBOAT4CLK4CCNCCDK8EGLN2 | |
| Hydrochloric Acid SCHEMBL16517183 | 0.78 | MBOAT4 (0.42) | MBOAT4CLK4CCNCCDK8VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481650-B2 | Process for the preparation of 2-trifluoromethyl isonicotinic acid and esters | HOFFMANN LA ROCHE INC. (US) | 2016-11-01 | — | — | US | disclosed |
| US-20150291530-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | HOFFMANN-LA ROCHE INC. (US) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291530-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | TAAR1, TAAR5, TSHR | MBOAT4 999/4885CLK4 4674/4885CCNC 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.