SCHEMBL17168507

SCHEMBL17168507

CC(C)c1ccc2c3c1-c1ncccc1C1=CN(C)C(C2)N13

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17168501 0.77 — —
SCHEMBL20626994 0.75 — —
SCHEMBL17171318 0.72 PDK2 (0.30) PDK2
SCHEMBL20627486 0.66 ALDH1A1 (0.31) —
SCHEMBL17168502 0.66 ALDH1A1 (0.31) —
SCHEMBL23638112 0.64 — —
SCHEMBL28043587 0.62 PTPRC (0.40) PDK2
SCHEMBL27107024 0.61 KCNH2 (0.37) PDK2
SCHEMBL12090332 0.56 GABRA1 (0.46) PDK2
SCHEMBL23207175 0.53 GABRA1 (0.43) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793066-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 — — US disclosed
US-10008679-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-26 — — US disclosed
US-20150295190-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150295190-A1 Organic Electroluminescent Materials and Devices EPCAM, ICMT, ORAI2 PDK2 1160/4885
US-10008679-B2 Organic electroluminescent materials and devices EPCAM, ICMT, ORAI2 PDK2 1160/4885
US-11793066-B2 Organic electroluminescent materials and devices EPCAM, ICMT, ORAI2 PDK2 1160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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