Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929274 | 1.00 | LMNA (0.39) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL12663200 | 0.87 | TDP1 (0.40) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL19741472 | 0.85 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL6696405 | 0.85 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL19741471 | 0.85 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL11146422 | 0.85 | LMNA (0.50) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL15096072 | 0.83 | LMNA (0.55) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL14554334 | 0.82 | LMNA (0.42) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL12330492 | 0.82 | LMNA (0.42) | LMNAL3MBTL1TDP1MGAMSI | |
| SCHEMBL1780664 | 0.82 | LMNA (0.42) | LMNAL3MBTL1TDP1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9410960-B2 | Method of diagnosing galactosemia in neonatal screening | STATENS SERUM INSTITUT (DK) | 2016-08-09 | — | — | US | disclosed |
| US-20150293111-A1 | METHOD OF DIAGNOSING GALACTOSEMIA IN NEONATAL SCREENING | STATENS SERUMINSTITUT (DK) | 2015-10-15 | — | — | US | disclosed |