Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741471 | 0.92 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL19741472 | 0.92 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL11146422 | 0.92 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL6696405 | 0.92 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL11145479 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL14554334 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL1780664 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL9246336 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL12330492 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EMGAM | |
| SCHEMBL17168358 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218129-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY SUGAR DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | DOW TORAY CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| US-9480630-B2 | Co-modified organopolysiloxane, emulsifier for water-in-oil emulsion, external use preparation, and cosmetic composition using the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-11-01 | — | — | US | disclosed |
| US-9475828-B2 | Organopolysiloxane and use thereof as surfactant, powder treatment agent, thickening agent of oil-based raw material or gelling agent. gel and emulsion compositions, as well as, preparations for external use and cosmetics comprising the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-10-25 | — | — | US | disclosed |
| US-20150011656-A1 | Co-Modified Organopolysiloxane, Emulsifier For Water-In-Oil Emulsion, External Use Preparation, And Cosmetic Composition Using The Same | DOW TORAY CO., LTD. (JP) | 2015-01-08 | — | — | US | disclosed |
| US-20140193353-A1 | Novel Organopolysiloxane Elastomer And Use Therefor | DOW CORNING TORAY CO. LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20140187649-A1 | Novel Liquid Organo Polysiloxane And Use Therefor | Dow Coming Toray Co., Ltd (JP) | 2014-07-03 | — | — | US | disclosed |
| US-20130210930-A1 | ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2013-08-15 | — | — | US | disclosed |
| US-20130177516-A1 | Cosmetic For Hair Containing Sugar Alcohol-Modified Silicone | DOW CORNING TORAY CO., LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011656-A1 | Co-Modified Organopolysiloxane, Emulsifier For Water-In-Oil Emulsion, External Use Preparation, And Cosmetic Composition Using The Same | H1-10, F12, H1-0 | LMNA 3366/4885L3MBTL1 3374/4885TDP1 3688/4885 |
| US-20170218129-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY SUGAR DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | SORD, GYS1, CD44 | LMNA 954/4885L3MBTL1 1486/4885TDP1 2988/4885 |
| US-20130210930-A1 | ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME | DDOST, RPN1, RPN2 | LMNA 633/4885L3MBTL1 3339/4885TDP1 4326/4885 |
| US-20140187649-A1 | Novel Liquid Organo Polysiloxane And Use Therefor | OR51E2, SORD, CUTA | LMNA 4007/4885L3MBTL1 2133/4885TDP1 3790/4885 |
| US-20130177516-A1 | Cosmetic For Hair Containing Sugar Alcohol-Modified Silicone | DPM1, FSCN1, CD44 | LMNA 873/4885L3MBTL1 4246/4885TDP1 4738/4885 |
| US-20140193353-A1 | Novel Organopolysiloxane Elastomer And Use Therefor | OR51E2, SOST, ELAVL1 | LMNA 3652/4885L3MBTL1 1162/4885TDP1 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.