Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717575 | 0.76 | L3MBTL1 (0.43) | L3MBTL1NPSR1TSHRMAPK1ATM | |
| SCHEMBL2984590 | 0.76 | DRD2 (0.56) | DRD2NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1717072 | 0.76 | DRD2 (0.56) | DRD2NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3602404 | 0.71 | KMT2A (0.45) | L3MBTL1TSHRMAPK1ATMALDH1A1 | |
| SCHEMBL2958088 | 0.67 | KMT2A (0.47) | L3MBTL1TSHRMAPK1ATMALDH1A1 | |
| SCHEMBL1415653 | 0.67 | ALDH1A1 (0.60) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2986632 | 0.66 | MAPT (0.45) | NPSR1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2986629 | 0.66 | MAPT (0.45) | NPSR1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL1717563 | 0.66 | MAPT (0.48) | L3MBTL1NPSR1MAPK1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL4501141 | 0.66 | KMT2A (0.46) | L3MBTL1TSHRMAPK1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656373-B1 | DERIVATIVES OF 2-ACYLAMINO-4-PHENYLTHIAZOLE, PREPARATION METHOD THEREOF AND USE OF SAME AS CHEMOKINEANTAGONISTS | SANOFI SA (FR) | 2012-01-18 | — | — | EP | claimed |