Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | CTSK | P43235 | 7/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027734 | 0.87 | MEN1 (0.44) | MEN1GAAKMT2ACA12CA1 | |
| SCHEMBL17175408 | 0.83 | MEN1 (0.46) | MEN1GAAKMT2ACA12CA1 | |
| SCHEMBL13480459 | 0.83 | MEN1 (0.52) | MEN1GAAKMT2ACA12CA1 | |
| SCHEMBL30373183 | 0.82 | ALDH1A1 (0.46) | ACHE | |
| SCHEMBL17175339 | 0.82 | MEN1 (0.45) | MEN1GAAKMT2ACA12CA1 | |
| SCHEMBL13767610 | 0.82 | MEN1 (0.48) | MEN1GAAKMT2ACA12CA1 | |
| SCHEMBL27696913 | 0.80 | CTSK (0.43) | CA1CA2CTSKCTSS | |
| SCHEMBL20953714 | 0.79 | SYK (0.60) | CTSSSYK | |
| SCHEMBL13942941 | 0.78 | PLA2G2C (0.43) | CTSKCTSS | |
| SCHEMBL15295107 | 0.77 | CTSK (0.44) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015157057-A1 | MACROCYCLES | LUMIPHORE, INC (US) | 2015-10-15 | — | — | WO | disclosed |