Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | TTPA | P49638 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 5/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717558 | 1.00 | LMNA (0.39) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL9285268 | 0.73 | LMNA (0.55) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL21131789 | 0.73 | LMNA (0.55) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL21931412 | 0.73 | LMNA (0.55) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL21931411 | 0.73 | LMNA (0.55) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL21929591 | 0.73 | LMNA (0.55) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL21929589 | 0.73 | LMNA (0.55) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL28448490 | 0.71 | LMNA (0.40) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL21754694 | 0.70 | LMNA (0.48) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL2635649 | 0.69 | LMNA (0.43) | LMNAMAPTMEN1KMT2AGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420610-B2 | Polyunsaturated compounds, method for preparing same and compositions containing the same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-04-16 | — | — | US | claimed |
| EP-1968993-B1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | FABRE PIERRE DERMO COSMETIQUE (FR) | 2012-01-11 | — | — | EP | claimed |
| US-20100168045-A1 | Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-07-01 | — | — | US | claimed |
| JP-2009519298-A | — | — | 2009-05-14 | — | — | JP | claimed |
| EP-1968993-A1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | Pierre Fabre Dermo-Cosmetique (FR) | 2008-09-17 | — | — | EP | claimed |
| WO-2007068745-A1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2007-06-21 | — | — | WO | claimed |
| US-8420610-B2 | Polyunsaturated compounds, method for preparing same and compositions containing the same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-04-16 | — | — | US | disclosed |
| EP-1968993-B1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | FABRE PIERRE DERMO COSMETIQUE (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20100168045-A1 | Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-07-01 | — | — | US | disclosed |
| EP-1968993-A1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | Pierre Fabre Dermo-Cosmetique (FR) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007068745-A1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168045-A1 | Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same | CBR3, CBR1, DECR1 | LMNA 1054/4885MAPT 4344/4885MEN1 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.