Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | NPPA | P01160 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613777 | 0.91 | NPY1R (0.55) | NAALAD2NPY1RNPY2RNPY4RBACE1 | |
| SCHEMBL29530540 | 0.87 | OPRM1 (0.49) | F2NPY1RNPY2RNPY4RERAP2 | |
| SCHEMBL9341200 | 0.86 | BACE1 (0.52) | NAALAD2F2NPY1RNPY2RNPY4R | |
| SCHEMBL9341178 | 0.86 | BACE1 (0.52) | NAALAD2F2NPY1RNPY2RNPY4R | |
| SCHEMBL30401037 | 0.86 | NPY1R (0.53) | F2NPY1RNPY2RNPY4RBACE1 | |
| SCHEMBL31650552 | 0.86 | NAALAD2 (0.58) | NAALAD2F2NPY1RNPY2RNPY4R | |
| SCHEMBL29531626 | 0.85 | OPRM1 (0.56) | F2BACE1BACE2 | |
| SCHEMBL29531082 | 0.85 | OPRM1 (0.56) | F2BACE1BACE2 | |
| SCHEMBL30512765 | 0.85 | BACE1 (0.59) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL31613782 | 0.85 | NPY4R (0.54) | NPY1RNPY2RNPY4RBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | Anglachem Inc. (CA) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | IDUA, GAA, MAN2B1 | NAALAD2 30/4885F2 4172/4885NPY1R 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.