SCHEMBL29531626

C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	4/20	0.56

▸	OPRD1	P41143	4/20	0.56

▸	F2	P00734	2/20	0.53

▸	BACE1	P56817	2/20	0.52

▸	BACE2	Q9Y5Z0	2/20	0.52

▸	KISS1R	Q969F8	3/20	0.51

▸	OPRK1	P41145	3/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29531082	1.00	OPRM1 (0.56)	OPRM1OPRD1F2BACE1BACE2
SCHEMBL29530540	0.96	OPRM1 (0.49)	OPRM1OPRD1F2BACE1BACE2
SCHEMBL29531229	0.95	OPRD1 (0.56)	OPRM1OPRD1F2BACE1BACE2
SCHEMBL29531643	0.95	OPRD1 (0.56)	OPRM1OPRD1F2BACE1BACE2
SCHEMBL29531061	0.92	OPRD1 (0.57)	OPRM1OPRD1BACE1BACE2KISS1R
SCHEMBL30522108	0.92	OPRM1 (0.56)	OPRM1OPRD1KISS1ROPRK1
SCHEMBL31243882	0.91	KISS1R (0.54)	OPRM1OPRD1KISS1ROPRK1
SCHEMBL29530787	0.91	OPRD1 (0.50)	OPRM1OPRD1F2BACE1BACE2
SCHEMBL29350420	0.89	OPRM1 (0.54)	OPRM1OPRD1OPRK1
SCHEMBL30974619	0.89	BACE1 (0.53)	OPRM1OPRD1F2BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12312390-B2	Rapid-acting insulin analogues of enhanced stability	CASE WESTERN RESERVE UNIVERSITY (US)	2025-05-27	—	—	US	disclosed
US-20220112262-A1	RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY	CASE WESTERN RESERVE UNIVERSITY	2022-04-14	—	—	US	disclosed