Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.57 |
| ▸ | IL23R | Q5VWK5 | 12/20 | 0.56 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17176533 | 0.88 | TFPI (0.62) | TFPIIL23RKISS1R | |
| SCHEMBL30414039 | 0.87 | NPY4R (0.57) | TFPIKISS1R | |
| SCHEMBL16508074 | 0.87 | IL23R (0.55) | TFPIIL23R | |
| SCHEMBL16508108 | 0.85 | NPY4R (0.57) | IL23RKISS1R | |
| SCHEMBL16509057 | 0.84 | NPY4R (0.54) | IL23RKISS1R | |
| SCHEMBL16508142 | 0.84 | KISS1R (0.58) | TFPIIL23RKISS1RKEAP1 | |
| SCHEMBL14479348 | 0.84 | NPY4R (0.58) | TFPIKEAP1 | |
| SCHEMBL16508093 | 0.84 | TFPI (0.63) | TFPIIL23RKISS1RKEAP1 | |
| SCHEMBL29994103 | 0.83 | TFPI (0.52) | TFPIIL23RKEAP1 | |
| SCHEMBL16507918 | 0.83 | NPY4R (0.61) | TFPIIL23RKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | Anglachem Inc. (CA) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | IDUA, GAA, MAN2B1 | TFPI 3118/4885IL23R 3331/4885KISS1R 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.