Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178358 | 0.94 | RXFP1 (0.38) | GPR6RXFP1DHODHSIRT2SMN1; SMN2 | |
| SCHEMBL17178401 | 0.94 | RXFP1 (0.38) | GPR6RXFP1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29379234 | 0.91 | MLYCD (0.40) | GPR6RXFP1DHODHTAS1R3TAS1R1 | |
| SCHEMBL15671140 | 0.91 | MLYCD (0.40) | GPR6RXFP1DHODHTAS1R3TAS1R1 | |
| SCHEMBL17178402 | 0.90 | RXFP1 (0.35) | GPR6RXFP1DHODHTAS1R3TAS1R1 | |
| SCHEMBL17178352 | 0.90 | RXFP1 (0.35) | GPR6RXFP1SLC2A1SLC2A3SIRT2 | |
| SCHEMBL16863608 | 0.88 | MLYCD (0.39) | GPR6RXFP1DHODHTAS1R3TAS1R1 | |
| SCHEMBL20187700 | 0.85 | NPC1 (0.37) | GPR6RXFP1DHODHTAS1R3TAS1R1 | |
| SCHEMBL17178350 | 0.85 | MLYCD (0.43) | GPR6RXFP1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL17178329 | 0.85 | MLYCD (0.43) | GPR6RXFP1DHODHTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-26 | — | — | US | disclosed |
| US-9718762-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | GPR6 4321/4885RXFP1 2936/4885DHODH 2171/4885 |
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | GPR6 4317/4885RXFP1 3170/4885DHODH 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.