Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178348 | 0.94 | GPR6 (0.36) | RXFP1GPR6SIRT2MAPTHPGD | |
| SCHEMBL17178352 | 0.94 | RXFP1 (0.35) | RXFP1GPR6SIRT2MAPTHPGD | |
| SCHEMBL17178350 | 0.90 | MLYCD (0.43) | RXFP1GPR6MAPTMLYCDRAB9A | |
| SCHEMBL17178401 | 0.90 | RXFP1 (0.38) | RXFP1GPR6SIRT2MAPTHPGD | |
| SCHEMBL1766956 | 0.89 | RXFP1 (0.39) | RXFP1SIRT2MAPTHPGDMLYCD | |
| SCHEMBL14844306 | 0.87 | GPBAR1 (0.40) | RXFP1MAPTMLYCDALDH1A1SMN1; SMN2 | |
| SCHEMBL17178402 | 0.86 | RXFP1 (0.35) | RXFP1GPR6SIRT2MAPTMLYCD | |
| SCHEMBL19513092 | 0.86 | MLYCD (0.41) | RXFP1GPR6MAPTMLYCDRAB9A | |
| SCHEMBL20233493 | 0.86 | MLYCD (0.41) | RXFP1GPR6MAPTMLYCDRAB9A | |
| SCHEMBL29379234 | 0.85 | MLYCD (0.40) | RXFP1GPR6MAPTMLYCDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-26 | — | — | US | disclosed |
| US-9718762-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | RXFP1 2936/4885GPR6 4321/4885SIRT2 261/4885 |
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | RXFP1 3170/4885GPR6 4317/4885SIRT2 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.