Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | TXK | P42681 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513092 | 0.83 | MLYCD (0.41) | MLYCDHDAC8ITKTXKLMNA | |
| SCHEMBL18356119 | 0.81 | MLYCD (0.40) | MLYCDHDAC8ITKTXKLMNA | |
| SCHEMBL299222 | 0.81 | MLYCD (0.41) | MLYCDLMNAPOLBSMN1; SMN2GFER | |
| SCHEMBL28494970 | 0.80 | HDAC8 (0.40) | MLYCDHDAC8MEN1KMT2ANPC1 | |
| SCHEMBL1766270 | 0.80 | SIRT2 (0.39) | MLYCDITKTXKLMNAPOLB | |
| SCHEMBL1766851 | 0.80 | SIRT2 (0.40) | MLYCDITKTXKLMNAPOLB | |
| SCHEMBL18355510 | 0.80 | MLYCD (0.39) | MLYCDHDAC8ITKTXKLMNA | |
| SCHEMBL22402096 | 0.78 | ITK (0.41) | MLYCDHDAC8ITKTXKLMNA | |
| SCHEMBL17178350 | 0.78 | MLYCD (0.43) | MLYCDHDAC8ITKTXKLMNA | |
| SCHEMBL17178352 | 0.77 | RXFP1 (0.35) | MLYCDITKLMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718762-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1808/4885HDAC8 768/4885ITK 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.