SCHEMBL17178761

SCHEMBL17178761

c1ccc(-c2ccc(-c3cc(-c4ccc(-n5c6ccc7ccccc7c6c6c7ccccc7ccc65)cc4)nc(-c4cccc5c4oc4ccccc45)n3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
KDM4E B2RXH2 4/20 0.37
ALDH1A1 P00352 4/20 0.37
MAPT P10636 4/20 0.37
HPGD P15428 4/20 0.37
MAPK1 P28482 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
KMT2A Q03164 1/20 0.34
PTGES O14684 1/20 0.34
PRKDC P78527 4/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ATM Q13315 2/20 0.33
GGPS1 O95749 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17179037 0.99 ALOX5 (0.40) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL17179042 0.94 ALOX5 (0.38) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL17179049 0.93 ALOX5 (0.38) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL24152140 0.92 ALOX5 (0.38) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL17179039 0.92 ALOX5 (0.38) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL17178759 0.91 ALOX5 (0.38) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL17178543 0.91 ALOX5 (0.38) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL17178558 0.91 ALOX5 (0.39) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL16811443 0.89 ALOX5 (0.37) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL19397647 0.89 ALOX5 (0.43) ALOX5KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10749119-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2020-08-18 US disclosed
US-20180033975-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-02-01 US disclosed
US-20180033975-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-02-01 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed
WO-2015156587-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10749119-B2 Plurality of host materials and organic electroluminescent device comprising the same SOD1, L3MBTL4, TELO2 ALOX5 1323/4885KDM4E 2303/4885ALDH1A1 1987/4885
US-20180033975-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TELO2, L3MBTL4 ALOX5 1400/4885KDM4E 2091/4885ALDH1A1 1915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.