Biphenyl

Biphenyl

SCHEMBL17182196

O=P(O)(O)Cl.O=P(O)(O)Cl.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 3/20 0.54
ALDH1A1 P00352 1/20 0.53
PTPN5 P54829 2/20 0.52
CA2 P00918 2/20 0.50
CA4 P22748 1/20 0.50
CA5A P35218 1/20 0.50
MMP8 P22894 2/20 0.48
MMP14 P50281 2/20 0.48
CA14 Q9ULX7 2/20 0.48
PTPN1 P18031 1/20 0.47
CYP1A2 P05177 1/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
SRC P12931 2/20 0.44
CFTR P13569 1/20 0.44
FDPS P14324 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1913481 1.00 ACP3 (0.54) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL11506188 0.94 ACP3 (0.54) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL1913599 0.89 ACP3 (0.50) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL263925 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL122229 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL342228 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL3763955 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL1945860 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL3727875 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4
Biphenyl SCHEMBL27485598 0.88 ALDH1A1 (0.60) ACP3ALDH1A1PTPN5CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284393-B2 Biomolecule-compatible, highly branched polymer and biomolecular-recognition surface KYUSHU UNIVERSITY (JP) 2016-03-15 US disclosed
US-20150299349-A1 BIOMOLECULE-COMPATIBLE, HIGHLY BRANCHED POLYMER AND BIOMOLECULAR-RECOGNITION SURFACE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-10-22 US disclosed