Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ACP3 | P15309 | 3/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP14 | P50281 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL342228 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL263925 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL3727875 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL27485598 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL3763955 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL11128267 | 0.97 | ALDH1A1 (0.56) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL28301373 | 0.97 | ALDH1A1 (0.56) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL356478 | 0.97 | ALDH1A1 (0.56) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL19244130 | 0.97 | ALDH1A1 (0.56) | ALDH1A1ACP3PTPN5CA2CA4 | |
| Biphenyl SCHEMBL28301372 | 0.97 | ALDH1A1 (0.56) | ALDH1A1ACP3PTPN5CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111500015-B | Halogen-free resin composition | 联茂(无锡)电子科技有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-117980409-A | Plateable poly (phenylene sulfide) and poly (phenylene ether) compositions | 高新特殊工程塑料全球技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113272367-B | Extruded capacitor films having high temperature performance, methods of manufacture, and articles comprising the same | 高新特殊工程塑料全球技术有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114830826-A | Photosensitive resin composition, cured film, organic EL display, display device, and method for producing cured film | 东丽株式会社 | 2022-07-29 | — | — | CN | disclosed |
| CN-113272367-A | Extruded capacitor films having high temperature properties, methods of manufacture, and articles comprising the same | 高新特殊工程塑料全球技术有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-106661218-B | High flow, high heat polycarbonate compositions | 沙特基础工业全球技术有限公司 | 2019-12-27 | — | — | CN | disclosed |
| US-8246737-B2 | Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer | KONICA MINOLTA OPTO, INC. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20110128478-A1 | POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF MANUFACTURING PROTECTIVE FILM FOR POLARIZING PLATE | KONICA MINOLTA OPTO, INC. (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20100069535-A1 | Cellulose Ester Optical Film, Polarizing Plate and Liquid Crystal Display Using the Same, Method of Manufacturing Cellulose Ester Optical Film, and Copolymer. | KONICA MINOLTA OPTO, INC. (JP) | 2010-03-18 | — | — | US | disclosed |
| CN-1948369-A | Preparation method of cellulose film | BEIJING PRINTING COLLEGE (CN) | 2007-04-18 | — | — | CN | disclosed |
| EP-0996678-A1 | HALOGEN-FREE FLAME-RETARDANT THERMOPLASTIC POLYESTER OR POLYAMIDE COMPOSITION | DSM N.V. (NL) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999002606-A1 | HALOGEN-FREE FLAME-RETARDANT THERMOPLASTIC POLYESTER OR POLYAMIDE COMPOSITION | DSM N.V. (NL) | 1999-01-21 | — | — | WO | disclosed |
| US-4739090-A | REACTING PHOSPHOROUS TRICHLORIDE, PENTAERYTHRITOL, AND ALKYL PHENOL IN PRESENCE OF CATALYST | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4187385-A | TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE | MITSUI TOATSU CHEMICAL, INC. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |