Biphenyl

Biphenyl

SCHEMBL342228

O=P(O)(O)O.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
ACP3 P15309 3/20 0.58
PTPN5 P54829 2/20 0.56
CA2 P00918 2/20 0.55
CA4 P22748 1/20 0.55
CA5A P35218 1/20 0.55
MMP8 P22894 2/20 0.52
MMP14 P50281 2/20 0.52
CA14 Q9ULX7 2/20 0.52
PTPN1 P18031 2/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
SRC P12931 2/20 0.48
CFTR P13569 1/20 0.48
FDPS P14324 1/20 0.47
CA9 Q16790 1/20 0.47
IDH1 O75874 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL263925 1.00 ALDH1A1 (0.60) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL3727875 1.00 ALDH1A1 (0.60) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL27485598 1.00 ALDH1A1 (0.60) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL1945860 1.00 ALDH1A1 (0.60) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL3763955 1.00 ALDH1A1 (0.60) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL11128267 0.97 ALDH1A1 (0.56) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL28301373 0.97 ALDH1A1 (0.56) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL356478 0.97 ALDH1A1 (0.56) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL19244130 0.97 ALDH1A1 (0.56) ALDH1A1ACP3PTPN5CA2CA4
Biphenyl SCHEMBL28301372 0.97 ALDH1A1 (0.56) ALDH1A1ACP3PTPN5CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551420-B1 CELLULOSE ESTER FILM AND METHOD OF MANUFACTURE EASTMAN KODAK CO (US) 1995-03-08 EP claimed
EP-0551420-A1 CELLULOSE ESTER FILM AND METHOD OF MANUFACTURE. EASTMAN KODAK CO (US) 1993-07-21 EP claimed
US-5219510-A Esterificating cellulose, melt casting, molecular orientation; photographic films EASTMAN KODAK COMPANY (US) 1993-06-15 US claimed
WO-1992005213-A1 CELLULOSE ESTER FILM AND METHOD OF MANUFACTURE EASTMAN KODAK COMPANY (US) 1992-04-02 WO claimed
JP-61197653-A None JP disclosed
WO-2026106021-A1 GEL-TYPE POLYMER ELECTROLYTE, LITHIUM METAL BATTERY COMPRISING SAME, AND METHOD FOR MANUFACTURING SAME 삼성에스디아이 주식회사 2026-05-21 WO disclosed
CN-116730807-B Direct cross coupling method of aryl phosphate and aryl bromide 南京工业大学 2024-05-24 CN disclosed
CN-116730807-A Direct cross coupling method of aryl phosphate and aryl bromide 南京工业大学 2023-09-12 CN disclosed
US-10865302-B2 Resin composition and use thereof ZEON CORPORATION (JP) 2020-12-15 US disclosed
US-10283711-B2 Method of producing organic EL ink and method of manufacturing organic EL device JOLED INC. (JP) 2019-05-07 US disclosed
US-20190040249-A1 RESIN COMPOSITION AND USE THEREOF ZEON CORPORATION (JP) 2019-02-07 US disclosed
US-20170207388-A1 METHOD OF PRODUCING ORGANIC EL INK AND METHOD OF MANUFACTURING ORGANIC EL DEVICE JOLED INC. (JP) 2017-07-20 US disclosed
EP-0611798-B1 RESIN COMPOSITION ASAHI CHEMICAL IND (JP) 1998-10-21 EP disclosed
EP-0551420-B1 CELLULOSE ESTER FILM AND METHOD OF MANUFACTURE EASTMAN KODAK CO (US) 1995-03-08 EP disclosed
EP-0611798-A1 RESIN COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1994-08-24 EP disclosed
EP-0551420-A1 CELLULOSE ESTER FILM AND METHOD OF MANUFACTURE. EASTMAN KODAK CO (US) 1993-07-21 EP disclosed
WO-1992005213-A1 CELLULOSE ESTER FILM AND METHOD OF MANUFACTURE EASTMAN KODAK COMPANY (US) 1992-04-02 WO disclosed
JP-S61197653-A FLAME-RETARDANT POLYPHENYLENE ETHER RESIN COMPOSITION MITSUBISHI GAS CHEM CO INC 1986-09-01 JP disclosed
US-4383067-A FILMS; HEAT RESISTANCE; EXTRUSION; POLY-IMIDAZOLES; POLYPARABANIC ACIDS EXXON RESEARCH & ENGINEERING CO. (US) 1983-05-10 US disclosed
EP-0071379-A1 Polymers characterized by 1,3-imidazolidine-1,3-diyl rings plasticized with phosphate esters EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-02-09 EP disclosed