Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22814023 | 0.82 | ALDH1A1 (0.50) | PPARGPPARDPPARAHSD17B10FABP4 | |
| SCHEMBL28450589 | 0.80 | EPHX2 (0.50) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL158056 | 0.78 | EPHX2 (0.48) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL158797 | 0.77 | ALDH1A1 (0.51) | EPHX2PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL27857048 | 0.77 | FAAH (0.49) | EPHX2CYP1A2MAPTCYP2C19BLM | |
| SCHEMBL25140 | 0.76 | ALDH1A1 (0.43) | PPARGPPARDPPARAMAPTHSD17B10 | |
| SCHEMBL14341514 | 0.76 | CA1 (0.44) | MMP2 | |
| SCHEMBL15238201 | 0.76 | EPHX2 (0.58) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL14341515 | 0.76 | CA1 (0.44) | MMP2 | |
| SCHEMBL15238203 | 0.76 | EPHX2 (0.58) | EPHX2TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150297749-A1 | LOW-DENSITY LIPOPROTEIN ANALOGUE NANOPARTICLES, AND COMPOSITION COMPRISING SAME FOR TARGETED DIAGNOSIS AND TREATMENT OF LIVER | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2015-10-22 | — | — | US | claimed |
| CN-117945938-A | Tris (hydroxymethyl) methylglycine and citrate lipids | 川斯勒佰尔公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114401942-B | Tris (hydroxymethyl) methylglycine and citrate lipids | 川斯勒佰尔公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117430538-A | Thioester cationic lipids | 川斯勒佰尔公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437767-B | thioester cationic lipids | 川斯勒佰尔公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115154620-A | CFTR MRNA compositions and related methods and uses | 夏尔人类遗传性治疗公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115135335-A | In vitro and in vivo gene delivery to immune effector cells using nanoparticles functionalized with Designed Ankyrin Repeat Proteins (DARPIN) | 生物技术细胞和基因治疗公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114401942-A | Tris (hydroxymethyl) methylglycine and citrate esters | 川斯勒佰尔公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114344275-A | Encapsulation of messenger RNA | 川斯勒佰尔公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114146063-A | Encapsulation of messenger RNA | 川斯勒佰尔公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-106456547-B | Encapsulation of messenger RNA | 川斯勒佰尔公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113423418-A | Treatment of cilia disease | 埃泽瑞斯公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113412273-A | Compositions and methods for treating primary ciliary dyskinesia | 川斯勒佰尔公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-112888451-A | Pump-free encapsulation of messenger RNA | 川斯勒佰尔公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112839639-A | Improved method for preparing mRNA loaded lipid nanoparticles | 川斯勒佰尔公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-112672761-A | Phosphate cationic lipids | 川斯勒佰尔公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-112533909-A | Vitamin cationic lipid | 川斯勒佰尔公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112437767-A | Thioester cationic lipids | 川斯勒佰尔公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-112424214-A | Cationic lipids comprising steroidal moieties | 川斯勒佰尔公司 | 2021-02-26 | — | — | CN | disclosed |