Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14085297 | 0.82 | MTNR1A (0.57) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL7960647 | 0.80 | AGXT (0.53) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL3982634 | 0.79 | TAAR1 (0.50) | CYP1A2CA1CA2CA9KCNH2 | |
| SCHEMBL1912735 | 0.77 | AGXT (1.00) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL17188578 | 0.76 | CA1 (0.44) | NPC1RAB9ACYP1A2CA1CA2 | |
| SCHEMBL2121782 | 0.76 | AGXT (0.57) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL11026671 | 0.76 | AGXT (0.57) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL9043883 | 0.76 | CA12 (0.57) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL28498268 | 0.74 | AGXT (0.47) | AGXTTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL17188570 | 0.74 | ACHE (0.46) | TDP1KDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9161922-B2 | Amine oxidase inhibitors | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |